—OK，I’ve had enough of it.I give up.—You can’tyour responsibilities. (2012·江苏，26)A. run of

—OK，I’ve had enough of it.I give up.
—You can’t your responsibilities. (2012·江苏，26)
A. run off with
B. run up against
C. run out of
D. run away from

A. run off withB. run up againstC. run out ofD. run away from解析：D解析　句意为：——好了，我已经受够了，我放弃。——你不能逃避你的责任。run away from逃离，躲避，符合句意。run off with带着……逃走，与……私奔；run up against偶遇；run out of用完。

我明天再问问老师，叫他解释下这个问题