in any case的用法

in any case的用法
in any case只能用于否定句吗?能不能列几句详细说明下啊

In any case.
在任何情况下,不管怎样.相当于anyhow
现举例如下,以供飨食：
In any case,it's usually quicker.
不管怎样,走路通常更快.
It's too late,in any case.
无论如何太晚了.
In any case they will preserve the skeleton.
无论如何他们将保全骨架.
You must keep the appointment in any case.
您无论如何也要赴约.
In any case he can not give up it.
他无论如何不会放弃它.