- Whats wrong with you, Madam? - Ive lost my valuable painting. But a week had gone by

- What's wrong with you, Madam?
- I've lost my valuable painting. But a week had gone by I knew it was missing.
A. while
B. since
C. until
D. before

A. whileB. sinceC. until(答案→)D. before解析：句意：——太太，你怎么啦？——我丢了我的贵重的油画。但是一周过去了，我才知道它丢了。A. while 当……时候； B. since 自从； C. until 直到； D. before在……之前；。根据knew，和had gone可知，在知道之前，那幅画已经丢了，故用连词before。故选D。

好好学习下