小鼠的遗传背景是什么意思

“As applied to a mutant mouse strain,genetic background refers to its genetic makeup (all its alleles at all loci),including other genetic material contributed by the embryonic stem cells,former genetic backgrounds,etc.That “other” genetic material can significantly influence a mutant strain’s phenotype.” ---Genetic Background:Understanding its importance in mouse-based biomedical research A Jackson Laboratory Resource Manual.
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